The skin epidermis has become the paradigm for exploring how a stratified epithelium develops in the embryo and how, in the adult, it maintains an inner layer of proliferating cells that gives ...

“The epidermis consists of keratinized stratified squamous epithelium, which is primarily comprised of keratinocytes,” said the study’s corresponding author, Masayuki Amagai.

The outer or inner boundaries of organs in the human body are lined with so-called epithelial sheets. These are layers of epithelial cells that can individually change their 3D shape -- which is ...

The epidermis is defined as a stratified squamous epithelium, consisting primarily of keratinocytes in progressive stages of differentiation (Revis and Seagle, 2006). Its prime function is to act as a ...

Epithelial stem cells play a central role in tissue homeostasis, wound repair, and carcinogenesis. Corneal epithelial stem cells have been demonstrated to reside in the limbal epithelium, while ...

Keratinocytes of the Upper Epidermis and Isthmus of Hair Follicles Express Hemoglobin mRNA and Protein. Journal of Investigative Dermatology , 2023; 143 (12): 2346 DOI: 10.1016/j.jid.2023.08.008 ...

The epidermis (outer layer of the skin) has three stem cell niches. ... In adult mice, the bulge SC only repopulate the epithelium in response to wounding and not homeostasis.

Skin has two main layers: the underlying dermis, made up of fibroblasts and other cells, and the outer epidermis, containing epithelial keratinocytes.

Next, we are extending the use of the approach to postnatal epidermis, to identify bona fide enhancers of tumor initiation and progression in the oncogenic Ras animal model. The complexity of our ...