A marathon Sunday of Week 5 produced plenty of winners and losers, with the 49ers and Bills among the teams sparking concerns.

Football feature is generating more watch and wager interest as the New Orleans Saints (2-2) tackle the Kansas City Chiefs (4 ...

Arizona Cardinals place kicker Chad Ryland, right, kicks a field goal against the San Francisco 49ers during the second half ...

QB Brock Purdy speaks to reporters after San Francisco's 24-23 loss to the Arizona Cardinals on Sunday at Levi's Stadium and ...

Tom Brady, FOX Sports lead NFL analyst, praised Arizona Cardinals quarterback Kyler Murray for leading a 13-point second-half ...

After the 49ers blew another game in the 4th quarter to an NFC opponent, the team was dealt another blow as Jake Moody ...

NFL legend Tom Brady recalled facing San Francisco 49ers quarterback Brock Purdy during his first career start in Week 14 of ...

Postgame, both Murray and Brock Purdy had a brief interaction following a hard-fought matchup. The two young quarterbacks, ...

The final takeaway came after the Cardinals took the lead with 1:37 to play. After a 15-yard gain, safety Jalen Thompson ...

The San Francisco 49ers were thought to be among the favorites to represent the NFC in the Super Bowl for a second straight year, but they haven't ...

Following the Cardinals' 24-23 win over the 49ers, Andrews posted a picture of her outfit from the game. Andrews was wearing an all-black outfit with a v-neck shirt, pants, and a belt. She also added ...

After swapping his cleats for a microphone, the spotlight during Sunday's game between the San Francisco 49ers and Arizona ...