Rising rates of cancer are going to come at a major cost, and it's looking more and more like the solution is going to have ...

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ASCO Presentation Supports SLS009 as a Potential Targeted Therapy for ASXL1 Mutated Colorectal Cancer – - 22,500 New Cases of Colorectal Cancer with High Microsatellite Instability per Year in the US: ...

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The identification and characterisation of kisspeptin represents a milestone in our understanding of the mechanisms underlying gonadotropin-releasing hormone (GnRH) neurosecretion.1,2 Kisspeptin is ...

Deleterious mutations were identified in 10.7% of women, including 6.1% in BRCA1/2 (5.1% in non-Ashkenazi Jewish patients) and 4.6% in other breast/ovarian cancer predisposition genes including CHEK2 ...

This is a valuable and rigorous study that addresses the question of what determines the spatial organization of endocytic zones at synapses. The authors use compelling approaches, in both Drosophila ...

A change to a single gene in the bacterium Yersinia pestis has enabled one of the world’s most notorious pathogens to survive for centuries.

Such mutations can be detrimental to its binding to the host receptor and were followed by additional compensatory mutations to recover, or even improve, its receptor binding. Momeni said the team was ...

Among cell lines with high impact frameshift mutations, all had mutations in protein position regions 581-582 and 642-643. Three out four had in addition high impact frameshift mutations in the region ...