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Thus, the glucocorticoid receptor is a double-edged sword in prostate cancer. Due to it promoting the development of drug resistance in prostate cancer, it was shown to have oncogenic effects.
Thus, the glucocorticoid receptor is a double-edged sword in prostate cancer. Due to it promoting the development of drug resistance in prostate cancer, it was shown to have oncogenic effects.
T-cell glucocorticoid receptor-deficient mice were generated using Lck promoter-driven, Cre recombinase-mediated excision of exon 2 of the glucocorticoid receptor gene.
Glucocorticoid receptors (GRs) are ligand-activated transcription factors that play a pivotal role in mediating the effects of endogenous and synthetic glucocorticoids.
This monoclonal antibody against the interleukin-2 receptor has been shown to be safe and effective in renal transplantation, and its use lowered the rates of rejection. 36 Daclizumab therapy is ...