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eLife9d
Glycogen Engineering Improves the Starvation Resistance of Mesenchymal stem cells and their Therapeutic Efficacy in Pulmonary Fibrosis
This valuable study presents a novel approach to enhance the therapeutic potential of mesenchymal stromal cells (MSCs) by genetically modifying their glycogen synthesis pathway, resulting in increased ...
C&EN2d
Elucidation of O-Glycosylation Structures of the β-Amyloid Precursor Protein by Liquid Chromatography−Mass Spectrometry Using Electron Transfer Dissociation and Collision ...
Accumulation and deposition of β-amyloid peptide, a major constituent in neuritic plaques are hallmarks of Alzheimer’s disease (AD) and AD-related neurodegenerative diseases. β-Amyloid (Aβ) is derived ...
PNAS19d
Identifying a large number of high-yield genes in rice by pedigree analysis, whole-genome sequencing, and CRISPR-Cas9 gene knockout | PNAS
Recently, a pedigree from crosses between different founding genotypes was used to fine-map QTLs in Arabidopsis (1, 9).The pedigree-based analysis combines linkage and association study ().A pedigree ...
PNAS13d
Multiomics of a rice population identifies genes and genomic regions that bestow low glycemic index and high protein content - PNAS
High-resistant starch (RS)/low-glutelin sbeIIb/Lgc1 lines were generated by CRISPR-Cas9-induced site-specific mutations in SBEIIb in an elite low-glutelin japonica rice cultivar ().According to this ...