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The extracellular matrix (ECM) of the cartilage is composed primarily of collagen type II and glycosaminoglycans (GAGs), and the constant breakdown and rebuilding of ECM components in the cartilage is ...
This hyaline-like cartilage more closely recreates the wear characteristics and durability of normal hyaline cartilage than the fibrous or fibrocartilage repair tissue formed by pluripotential ...
Cartilage injuries may be caused by trauma, biomechanical imbalance, or degenerative changes of joint. Unfortunately, cartilage has limited capability to spontaneous repair once damaged and may lead ...
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