In a new study, Yale researchers offer insight into leptin, a hormone that plays a key role in appetite, overeating, and obesity. Their findings advance knowledge about leptin and weight gain, and ...

McGavock Professor and professor of molecular physiology ... may exert lasting effects on the structure and function of circuits that control energy balance. Leptin is a hormone that, in adults ...

Leptin is a molecule that is well known in obesity research; it is released by white fat cells, reducing appetite and contributing to the maintenance of healthy levels of blood sugar and weight. The ...

Here, we characterize two novel homozygous leptin variants that yielded antagonistic ... Details on protein structure modeling, activity, binding, internalization, and competition studies are ...

Friedman's laboratory at the Rockefeller University cloned the leptin gene in 1994. But now Bowen Tan, Kristina Hedbacker, and other researchers in Friedman's Laboratory of Molecular Genetics have ...

A single family has been described in which obesity results from a mutation in the leptin-receptor gene (LEPR), but the prevalence of such mutations in severe, early-onset obesity has not been ...

BOSTON – Leptin, a molecule linked with obesity, may play a crucial role in predicting poor prognosis from thyroid cancer, at least in the Middle Eastern region of the world, according to data ...

The new study shows that leptin toggles a runner’s desire by cutting access to a reward chemical — dopamine — in one of the brain’s motivation centers, the ventral tegmental area.