After swapping his cleats for a microphone, the spotlight during Sunday's game between the San Francisco 49ers and Arizona ...

The San Francisco 49ers were thought to be among the favorites to represent the NFC in the Super Bowl for a second straight year, but they haven't ...

Half of the 10 Sunday afternoon games on the Week 5 NFL schedule are divisional matchups, but oddly, none of them features a ...

SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...

The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

An Aussie had a career day, and the rookie throwers are starting to make their mark as the NFL reached week five.

The 49ers' biggest issue was something that's plagued them all season: They had six trips to the red zone and scored just one ...

Kyle Juszczyk took a shot at Niner beat reporter Grant Cohn, implying that a married man is gay. Whether Juszczyk was saying ...

The only game in Week 5 between teams with winning records, this matchup is the "Stefon Diggs Bowl," as the Texans’ wideout plays his former team for the first time. An NFL All-Pro four consecutive ...

The record-breaking heat for a San Francisco 49ers game at Levi’s Stadium has sent fans at the game down to the concourses.

The San Francisco 49ers are preparing for their Week 5 matchup against the Arizona Cardinals under challenging weather ...