The Vikings led the San Francisco 49ers 3-0 early in the second quarter ... who caught the pass right at the midfield logo. The All-Pro wideout showed off the perfect blend of footwork, speed ...

After swapping his cleats for a microphone, the spotlight during Sunday's game between the San Francisco 49ers and Arizona ...

The San Francisco 49ers were thought to be among the favorites to represent the NFC in the Super Bowl for a second straight year, but they haven't ...

Half of the 10 Sunday afternoon games on the Week 5 NFL schedule are divisional matchups, but oddly, none of them features a ...

SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...

The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

San Francisco's defense rebounded against the Patriots but faces a tougher test in Murray's dynamic playmaking ability. Brock ...

Tagovailoa sustained at least the third concussion of his career in Week 2’s 31-10 loss to the Buffalo Bills. On Sept. 17, ...

49ers' defense allowing 6.11 yards per play, third-worst in NFL and fourth-worst in franchise history through three games. Hargrave's absence leaves a gap in interior pressure, with newcomers Collins ...

An Aussie had a career day, and the rookie throwers are starting to make their mark as the NFL reached week five.

Why San Francisco 49ers changed their uniform for NFL Week 5 game against Arizona Cardinals Sunday, and why it's not the ...

Despite not being available to 11M DirecTV customers, ESPN‘s Monday Night Football was still off to a strong start with its 49ers-Jets season opener. The 49ers squashed Aaron Rodgers’ return ...