When is Holland America’s 21-day Panama Canal cruise? The cruise will depart on April 11, 2027, from Fort Lauderdale, Florida, aboard the line’s 2,106-guest Nieuw Amsterdam ship.

Overview Part of Royal Caribbean's Radiance class, the Brilliance of the Seas carries 2,188 mostly American passengers. The decor helps remind passengers they are aboard a ship (it's often easy to ...