When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...
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Study reveals ATM kinase as the key driver of replicative senescence
After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the protective ...
We have long struggled to determine how the first living organisms on Earth came together. Now, surprising evidence hints ...
The protein, reverse transcriptase, has become an essential tool for making DNA copies of RNA.
Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...
Mitochondrial DNA (mtDNA) exhibits a degree of resistance to mutagenesis under genotoxic stress, and this study on the mitochondrial Transcription Factor A (TFAM) presents valuable data concerning the ...
In eukaryotic cells, present in animals, plants, fungi and protists, most DNA is concentrated in the nucleus. This membrane-bound organelle serves as the command center of the cell, protecting the ...
DNA replication is a semi-conservative process in which half of the newly synthesized strands (daughters) are derived from the original strands (mothers). The confirmation of semi-conservative ...
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