A potential strategy introduces an entirely new type of therapy capable of addressing previously ‘undruggable’ targets within the cells.

AI model reveals the structural secrets of misfolded proteins. A new artificial intelligence (AI) tool has provided critical ...

Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization ...

Researchers have developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure. The therapy both prompts the immune system to ...

Nature has developed a unique structure as a scaffold for almost all nerve cells: the membrane-associated periodic skeleton ...

In 2021, research led by Ryan Flynn, MD, Ph.D., and his mentor, Nobel laureate Carolyn Bertozzi, Ph.D., opened a new chapter ...

Department of Toxicology, School of Medicine and Public Health and Department of Pharmacology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China ...

View Full Profile. Learn about our Editorial Policies. “We measured every possible mutation in these [500 or so] protein [domains],” said Antoni Beltran, a molecular biologist at the Center for ...

2024), demonstrating remarkable success in predicting protein complexes and multi-domain assemblies. However, the performance of AI-based tools like AlphaFold is inherently constrained by the ...