Scientists at the Faculty of Medicine have now developed an innovative numbering system for the GAIN domain, a protein domain common to all adhesion GPCRs. It should help to elucidate the role of ...

Using the CRISPR/Cas9 genome-editing system to mutate the gene regions encoding particular protein domains could result in a new and more efficient method to screen for druggable protein targets ...

Each cell in your body relies on precise communication with other cells to function properly. At the center of this process ...

Nitrase Therapeutics Inc. has unveiled a protein named glyoxalase domain-containing protein 4 (GLOD4) responsible for catalyzing selective protein nitration. This reflects a new class of enzymatic ...

Glyoxalase Domain-containing Protein 4 (GLOD4), the First Identified in a New Class of Enzymes Called Nitrases, Generates Nitrated ...

In the inactive conformation, the a-subunit of the G protein binds to GDP and is bound to a beta-gamma complex (a). Upon receptor activation by its ligand, there is an exchange of GDP for GTP (b).