Much of the difficulty of determining the contributions of individual residues to protein structure and function stems from the need to generate and evaluate a large number of mutants. The ...

New research by scientists at the University of Toronto and the Structural Genomics Consortium has deepened our understanding ...

In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read ...

Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization ...

Discover how scientists imaged the Parkinson’s protein PINK1, unlocking insight into its role in mitochondrial quality ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...

The latest version of Google DeepMind and Isomorphic Labs’ AlphaFold model can predict the structure and relationships not only of proteins, but “all of life’s molecules”, according to its ...

Discover how a flexible protein can rearrange itself to multitask efficiently, revolutionizing medicine, agriculture, and ...

In today’s digital transformation era, scientific inquiry is increasingly guided by computational tools that uncover intricate biological mechanisms. Sarika Kondra, along with co-authors Feng Chen, ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

After you eat a meal, zinc is taken up by the cells of your body. Inside each cell, zinc binds to proteins to support their structure and function. Researchers estimate that up to 10% of all proteins ...