Human genetics provides clues to why DNA regulatory regions get 'loopy'
DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...
The EMBO Journal1mon
Structure of the Nipah virus polymerase complex
The RNA polymerase complex of the Nipah virus is responsible for both replication and transcription of the viral RNA genome. This study elucidates the structure of the RNA polymerase in complex with ...
eLife8mon
Ligand Response of Guanidine-IV riboswitch at Single-molecule Level
State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China Shanghai Artificial Intelligence Laboratory, Shanghai ...
Frontiers2y
The Transcription Factor Pou3f1 Sheds Light on the Development and Molecular Diversity of Glutamatergic Cerebellar Nuclear Neurons in the Mouse
Riboprobes were produced using the SP6 or T7 RNA polymerase (#EP0133 and #EP0111 ... we explored the possible co-localization of Pou3f1 with these two transcription factors. The present study ...
Frontiers2y
Investigation on Natural Infection of Covert Mortality Nodavirus in Large Yellow Croaker, Larimichthys crocea
The second-step PCR was performed in a similar way as the first-step PCR except for the incubation for the reverse transcription. Two target CMNV-specific RNA-dependent RNA polymerase (RdRp) gene ...