A marathon Sunday of Week 5 produced plenty of winners and losers, with the 49ers and Bills among the teams sparking concerns.

With the San Francisco 49ers (2-3) and the Seattle Seahawks (3-2) squaring off on Oct. 10 at Lumen Field, Brock Purdy and ...

Get ready for an exciting Week 6 showdown as Jauan Jennings takes on Tariq Woolen and the Seahawks' secondary. Check out ...

With the San Francisco 49ers (2-3) and the Seattle Seahawks (3-2) squaring off on Oct. 10 at Lumen Field, Brock Purdy and ...

San Francisco leaders pushed signs of progress in Union Square, promising a safe city as they honored first responders who ...

San Francisco leaders pushed signs of progress in Union Square, promising a safe city as they honored first responders who ...

Tom Brady, FOX Sports lead NFL analyst, praised Arizona Cardinals quarterback Kyler Murray for leading a 13-point second-half ...

After the 49ers blew another game in the 4th quarter to an NFC opponent, the team was dealt another blow as Jake Moody ...

Disappointment was in the air Sunday after the San Francisco 49ers blew a 13-point halftime lead in their 24-23 loss to the Arizona Cardinals at ...

NFL legend Tom Brady recalled facing San Francisco 49ers quarterback Brock Purdy during his first career start in Week 14 of ...

Postgame, both Murray and Brock Purdy had a brief interaction following a hard-fought matchup. The two young quarterbacks, ...