本期推荐：肿瘤微环境(TME)中癌症相关成纤维细胞(CAFs)的激活机制一直是研究难点。中国研究团队发现CXCL12/STAT3信号轴是正常 ...

编辑推荐：本研究针对获得性纯红细胞再生障碍(PRCA)的遗传异质性难题，通过全外显子测序(WES)和靶向测序技术，揭示了STAT3、TET2、POT1等基因突变与PRCA亚型的关联，首次提出基于STAT3和克隆造血 ...

3月28日，中南大学湘雅医院研究团队在期刊《Cell Death&Disease》上发表了研究论文，题为“CSF3R-AS promotes hepatocellular carcinoma progression and sorafenib resistance through the CSF3R/JAK2/STAT3 positive feedback loop ...

We found that lipopolysaccharide treatment triggered neutrophil activation in an HPK1-dependent manner. HPK1 enhanced intrinsic NF-κB/STAT3/p38-MAPK pathways and gasdermin D cleavage, leading to ...