A marathon Sunday of Week 5 produced plenty of winners and losers, with the 49ers and Bills among the teams sparking concerns.

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Jerome Ford and Zamir White may have been coveted players in fantasy football drafts, but it may be time to release them from your fantasy rosters.

With the San Francisco 49ers (2-3) and the Seattle Seahawks (3-2) squaring off on Oct. 10 at Lumen Field, Brock Purdy and ...

Football feature is generating more watch and wager interest as the New Orleans Saints (2-2) tackle the Kansas City Chiefs (4 ...

The game against the Arizona Cardinals marked the second time this season that San Francisco (2-3) blew a double-digit lead ...

The San Francisco 49ers were thought to be among the favorites to represent the NFC in the Super Bowl for a second straight year, but they haven't ...

The 49ers' biggest issue was something that's plagued them all season: They had six trips to the red zone and scored just one ...

Former Oregon Ducks and current San Francisco 49ers defensive back Deommodore Lenoir scooped the ball after a blocked field goal attempt and ran for a 60-yard t ...

The 49ers just blew another 10-point fourth quarter lead and lost 24-23 to the Arizona Cardinals. Now the 49ers are 2-3. Here ...

The FNIA crew discuss the San Francisco 49ers' loss to the Arizona Cardinals in Week 5, analyzing how Kyle Shanahan's squad ...

The Ravens (-6.5) have won three games in a row, the latest being a 41-38 thriller in overtime over Cincinnati after scoring ...