Brock Purdy had two costly interceptions against the Cardinals, resulting in a disappointing one-point loss for the 49ers.

After Arizona's defense forced a three-and-out, the Cardinals received possession. After finding tight end Trey McBride on a ...

This was a stark contrast to the other offense in the game led by Deshaun Watson. The Commanders held Watson and the ...

Despite being largely considered the best overall quarterback in the NFL, Chiefs quarterback Patrick Mahomes is just the QB16 ...

Former Oregon Ducks and current San Francisco 49ers defensive back Deommodore Lenoir scooped the ball after a blocked field goal attempt and ran for a 60-yard t ...

Tom Brady awards Arizona Cardinals QB Kyler Murray with the LFG Player of the Game after his dominant performance against the ...

San Francisco 49ers quarterback Brock Purdy's 53-yard connection with wide receiver Brandon Aiyuk comes on the 49ers' first play from scrimmage.

San Francisco 49ers quarterback Brock Purdy's 13-yard connection with wide receiver Juan Jennings gets the 49ers into red zone for second time.

The 49ers just blew another 10-point fourth quarter lead and lost 24-23 to the Arizona Cardinals. Now the 49ers are 2-3. Here ...

Tom Brady, FOX Sports lead NFL analyst, praised Arizona Cardinals quarterback Kyler Murray for leading a 13-point second-half ...

We’re now five weeks into the NFL season, and there are far more questions than answers for the San Francisco 49ers.

What's the Arizona Cardinals vs San Francisco 49ers score? Follow our live game updates for the latest news, analysis from ...