SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...

The San Francisco 49ers appear to be back. The team entered Week 4 with a 1-2 record and desperately needed a win over the ...

San Francisco's defense rebounded against the Patriots but faces a tougher test in Murray's dynamic playmaking ability. Brock ...

After missing the first three games of the season, San Francisco 49ers star running back Christian McCaffrey is set to ramp ...

Who will move on to 2-0 when the San Francisco 49ers (1-0) and Minnesota Vikings (1-0) square off? Christian McCaffrey didn't play, but the 49ers didn't skip a beat when they crushed the New York ...

The San Francisco 49ers opened up the 2024 season with a 32-19 win over the New York Jets on "Monday Night Football." The San Francisco 49ers secured their first preseason win, taking down the ...

The 49ers bounce back with a dominant victory over the Patriots, led by Warner's pick-6 and Purdy's deep passes.

The San Francisco ... in San Francisco’s Week 1 win against the New York Jets. He will now miss at least the next four games, first eligible to return in Week 6. On Friday, 49ers head coach ...

SportsLine's advanced computer model locked in the top NFL office pool picks for Week 5 of the 2024 NFL schedule ...

The Minnesota Vikings will host the San Francisco 49ers this Sunday at U.S. Bank Stadium ... Paramount+ still offers a one-week free trial — so new subscribers can sign up to watch this weekend ...

Brock Purdy threw a touchdown pass, Fred Warner returned an interception for a score and the San Francisco 49ers snapped a two-game skid by beating the New England Patriots 30-13 on Sunday.