Objective To determine how distinct combinations of resistance training prescription (RTx) variables (load, sets and frequency) affect muscle strength and hypertrophy. Data sources MEDLINE, Embase, ...

1 Health and Rehabilitation Sciences Research Institute, University of Ulster, Newtownabbey, UK 2 Sports Institute of Northern Ireland and Ulster Rugby, Newtownabbey, UK Correspondence to C M Bleakley ...

WASHINGTON, Nov 3 (Reuters) - U.S. manufacturing contracted for an eighth straight month in October as new orders remained subdued, and suppliers were taking longer to deliver materials to factories ...

Background: Myh14, encoding non-muscle myosin IIC (NMIIC), is a proposed negative regulator of isoproterenol (ISO)-induced cardiac hypertrophy. ISO upregulated mRNA transcript level of Myh14 in NRVM.

The Golgi apparatus transports and modifies proteins in eukaryotic cells. How have scientists studied dynamic protein movements through the Golgi? One of the principal observations by Rothman's group ...

Introduction: Inhibiting contractility by targeting cardiac myosin is an effective treatment for patients with hypertrophic cardiomyopathy (HCM). Aficamten (Afi), a second in class myosin inhibitor, ...