You may not have noticed, but transgenic fish made a big splash last month. GloFish—a brand of transgenic zebrafish that fluoresces red under ultraviolet light—are currently on sale in ...

Zebrafish model for an ultra-rare genetic disease reveals two promising drug candidates by Jeff Hansen, University of Alabama at Birmingham edited by Stephanie Baum , reviewed by Robert Egan ...

In a study published in EMBO Molecular Medicine, Alexander and Dowling now show that their mutant zebrafish have weakened muscles and other symptoms that mirror human XMEA disease. With this simple ...

Molecular signals after severing an axolotl arm direct the remaining cells how to regrow the limb, offering potential ...

Species: Mouse Genes: MAPT Mutations: MAPT P301L Modification: MAPT: Transgenic Disease Relevance: Alzheimer's Disease, Frontotemporal Dementia Strain Name: Thy1-hTau.P301L Genetic Background: FVB/N ...

We generated 27 zebrafish mutants with presumptive protein-truncating mutations or specific missense variants corresponding to autism-risk alleles in 17 human genes. We observed baseline and ...

To monitor the turnover and maintenance of microglia in adult zebrafish brain, we employed microglia-specific TgBAC(ccl34b.1:eGFP) transgenic reporter line (Wu et al., 2020) and performed EdU ...

Bisphenol A (BPA) is a well-known endocrine-disrupting chemical (EDC) that has estrogenic activities. In addition to disrupting reproductive development and function via estrogenic signaling pathways, ...

Metal elements in aquatic environments are often transformed into metal sulfide nanoparticles (MSNPs), which are generally considered less toxic due to their low solubility. However, emerging evidence ...