JSTOR Daily

High cGMP Synthetic Activity in Carp Cones

Cones show briefer light responses than rods and do not saturate even under very bright light. Using purified rod and cone homogenates, we measured the activity of guanylate cyclase (GC), an enzyme ...
JSTOR Daily

Sildenafil and Cardiomyocyte-Specific cGMP Signaling Prevent Cardiomyopathic Changes Associated with Dystrophin Deficiency

We recently demonstrated early metabolic alterations in the dystrophin-deficient mdx heart that precede overt cardiomyopathy and may represent an early "subclinical" signature of a defective nitric ...
Monthly Prescribing Reference

Chromosome 12 Mutation Linked to Familial Diarrhea

(HealthDay News) – An activating mutation in GUCY2C, encoding guanylate cyclase C (GC-C), is thought to cause a novel familial diarrhea syndrome seen in a Norwegian family. Torunn Fiskerstrand, MD, ...
Business Wire

Artiva Biotherapeutics Establishes U.S. Research and Manufacturing Facility for NK Cell Therapy Pipeline Development and Clinical Supply

52,000-square-foot corporate headquarters in San Diego with R&D and GMP manufacturing center to open in 2022 Builds on current capability at Artiva’s partner GC LabCell’s facility in Republic of Korea ...
PharmTech

Testing Laboratory Receives Warning Letter

FDA issued a warning letter to contract testing laboratory, Adamson Analytical Laboratories, for CGMP violations. FDA issued a warning letter to contract testing laboratory, Adamson Analytical ...