(NASDAQ: AIRG), a leading provider of wireless connectivity solutions, today announced the launch of the NimbeLink Skywire™ ...

Swiss-led study using single-cell RNA sequencing finds early immune activation in fibroblasts may be a key trigger in the ...

Notably, CD74⁺ B cells were enriched within TLS, particularly during early developmental stages. Mapped the spatially in situ developmental trajectory of CD74⁺ B cells and uncovered the dynamic ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled "Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 ...

imageimageCD47-amyloid-β-CD74 signaling is a key driver of adaptive immunosuppression in sepsis, suppressing B cells and impairing immunity. Blocking this pathway restores immune function and improves ...

CD74-KO mice undergoing CLP surgery showed a lower survival rate, supporting the hypothesis that CD74 blockade leads to B-cell suppression (Appendix Fig. S21). Figure 8 . Blocking CD47-amyloid-β ...

Our work suggests that testing for CD74 levels – which signal that the immune system is 'just right' to fight the tumor – could widen access to immunotherapy.

CD74 protein levels can predict immunotherapy response in bowel cancer, regardless of subtype. This discovery could expand treatment eligibility to patients with the proficient subtype, who ...