The most significant injury for the 49ers is to their franchise quarterback, Brock Purdy. He’s expected to miss several games ...

The San Francisco 49ers will be without their quarterback in Week 2 vs. the New Orleans Saints, but signs on their star RB ...

Brock Purdy will not be on hand for the San Francisco 49ers when they take on the New Orleans Saints. Neither will George Kittle after he was placed on Injured ...

Sophia Culpo said her sister Olivia Culpo's baby, Colette, is Christian McCaffrey's 'twin' in an exclusive interview with ...

The 49ers enter Sunday’s game in New Orleans seeking to open a season with back-to-back road wins like in 2019, ’21 and ’23.

The San Francisco 49ers prepare for Week 2 with one key change, Mac Jones will be the quarterback. The signal-caller has opened up about the possibility in front of him.

How do you see this one playing out? Our staff writers made their picks for Week 2's final score and bold predictions in Saints vs. 49ers: ...

Is Jauan Jennings playing Week 2? Fantasy football injury update and outlook for Week 2 of 2025. Read the latest Jauan Jennings injury report and news.

The New Orleans Saints must run the ball effectively for any realistic chance of beating the San Francisco 49ers ...