The most significant injury for the 49ers is to their franchise quarterback, Brock Purdy. He’s expected to miss several games ...

The San Francisco 49ers will be without their quarterback in Week 2 vs. the New Orleans Saints, but signs on their star RB ...

Get the latest 49ers vs. Saints Week 2 betting preview with injury updates, data-driven predictions, projected box score ...

San Francisco 49ers star Christian McCaffrey missed practice Friday and was being listed as questionable for the team's Week ...

Christian McCaffrey popped up on the injury report on Thursday and didn't practice Friday. Will he play Sunday?

The San Francisco 49ers begin their quest to a Supe Bowl with the season-opener against the Seattle Seahawks today. Find out ...

Christian McCaffrey reportedly is "good to go" for San Francisco's Week 1 matchup against the Seattle Seahawks.

San Francisco 49ers star running back Christian McCaffrey has been dealing with a calf injury that began to worry the entire ...

McCaffrey may be healthy enough to be a full participant on days when he is limited, and he may sit out entirely on days when ...

San Francisco 49ers star Christian McCaffrey has been added to the team's injury report with a calf issue. This comes just ...

The New Orleans Saints are just two days away from their second game of the 2025 National Football League regular season. In the buildup to the matchup with the ...

San Francisco 49ers star Christian McCaffrey is questionable for the season opener after injuring his calf at practice ...