USA Today's NFL experts make their picks for a Week 2 showdown between the New Orleans Saints and San Francisco 49ers ...

The Los Angeles Chargers and Buffalo Bills were both underdogs in Week 1 and, thanks to stellar play from their respective ...

The San Francisco 49ers (1-0) hit the road to match up against the New Orleans Saints (0-1) at Caesars Superdome on Sunday, ...

The San Francisco 49ers, led by quarterback Mac Jones, face the New Orleans Saints, led by quarterback Spencer Rattler, on ...

That was the case last week in the 2025 season opener when they took a nine-point lead into the fourth quarter against the ...

The 49ers enter Sunday’s game in New Orleans seeking to open a season with back-to-back road wins like in 2019, ’21 and ’23.

Jauan Jennings will be a game-time decision on Sunday as the 49ers take on the Saints, as he's suffering from a shoulder ...

Learn which TV channel or how to live stream the NFL Week 2 New Orleans Saints and San Francisco 49ers game, Sunday, Sept. 14 ...

The San Francisco 49ers will be without their quarterback in Week 2 vs. the New Orleans Saints, but signs on their star RB ...

The first thing Staley did as Saints DC was trade for 330-pound nose guard Davon Godchaux, an absolute beast who is a ...

NEW ORLEANS (WVUE) - The 49ers opened as a 6.5-point favorite over the Saints on Sunday night. But, when it became apparent that Niners quarterback Brock Purdy and tight end George Kittle would miss ...

The San Francisco 49ers are going to be shorthanded when they take on the New Orleans Saints. However, they are still favorites, and there is no reason for them to lose. Still, when others go down, ...