With Brock Purdy ruled out of Sunday's game against the New Orleans Saints, the San Francisco 49ers have named Mac Jones ...

Preview the San Francisco 49ers' NFL Week 2 matchup with the Saints, including live stream, TV channel, odds, and game ...

Preview the New Orleans Saints' NFL Week 2 matchup with the 49ers, including live stream, TV channel, odds, and game ...

The 49ers enter Sunday’s game in New Orleans seeking to open a season with back-to-back road wins like in 2019, ’21 and ’23.

The San Francisco 49ers and New Orleans Saints meet Sunday in Week 2 at Caesars Superdome in New Orleans, Louisiana.

Find single game tickets to the San Francisco 49ers vs. New Orleans Saints NFL Week 2 matchup on Sunday, September 14, 2025 ...

NFL Week 2 odds, picks, predictions, TV channel, streaming information for Sunday football game between San Francisco 49ers ...

The New Orleans Saints have another tough NFC foe ahead of them. Kellen Moore's team took a close defeat in Week 1, but there ...

USA Today's NFL experts make their picks for a Week 2 showdown between the New Orleans Saints and San Francisco 49ers ...

Mac Jones will start for the San Francisco 49ers against the New Orleans Saints. Brock Purdy is out with a toe injury. Coach ...

The New Orleans Saints are going to take on an injury-riddled San Francisco 49ers team this weekend. San Francisco isn't going to have quarterback Brock Purdy o ...

Everything you need to know on how to watch New Orleans Saints vs San Francisco 49ers NFL Game - team news, livestream, TV channel, and start time.