SKY-0515, an oral drug, safely lowers huntingtin in people with HD and may also reduce PMS1. This could offer a possible two-pronged approach to treat HD. SKY-0515 is now being tested in a larger ...

We’re proud to announce Nicolo Zarotti as a 2025 HDBuzz Prize winner! A new case study shows Acceptance & Commitment Therapy ...

We’re proud to announce Jenna Hanrahan as a 2025 HDBuzz Prize winner! People with HD may be unaware of their symptoms, not out of denial but due to real changes in the brain. MRI scans give new clues ...

Prilenia has publicly shared the data from the PROOF-HD study over the course of the last few years, at HD conferences and other research events. This recent paper reiterates the main points – overall ...

We’re proud to announce Eva Woods as a 2025 HDBuzz Prize winner! Scientists spotted small brainwave changes in people with HD before symptoms begin. These early electrical “whispers” of HD could help ...

This month’s Huntington’s disease (HD) research roundup spans work from the dinner table to DNA repair. Scientists explored whether eating on a schedule could help clear toxic proteins, uncovered ...

Two research teams have uncovered how a small change in FAN1, a DNA repair protein, can speed up Huntington’s disease (HD). In back-to-back papers in Nature Communications, they show how a single ...

Two studies from the same research group have helped to provide some important blueprints for Huntington’s disease (HD) research, helping us to more clearly understand what the toxic fragment form of ...

We’re “Falling Into Hope”! Our goal: raise $30,000 by Oct 28 to keep HDBuzz independent and growing. Help us deliver trusted, unbiased HD research updates in this pivotal year, and beyond. This Fall, ...

Carly Desmond is a PhD Candidate at McMaster University in Hamilton, Ontario, Canada. Working under the supervision of Dr. Ray Truant, her research focuses on understanding the normal and pathological ...