The San Francisco 49ers were thought to be among the favorites to represent the NFC in the Super Bowl for a second straight year, but they haven't ...

The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

After swapping his cleats for a microphone, the spotlight during Sunday's game between the San Francisco 49ers and Arizona ...

But the first series — a two-play, 72-yard touchdown drive, saw Campbell burned on a chunk-yard pass and then a 50-yard ...

For the first month of the season, the San Franciso 49ers’ special teams unit has struggled. Whether it’s a blocked punt, a ...

The 49ers' biggest issue was something that's plagued them all season: They had six trips to the red zone and scored just one ...

SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...

Nine teams scored 30-plus points and three games combined for 60 or more. Captain Kirk Cousins threw for a whopping 509 ...

The Madden Curse has once again cast its shadow, this time over San Francisco 49ers superstar Christian McCaffrey (CMC).

The 49ers could've closed this game out 10 different ways. Instead they ended it looking as burned as the Levi's fans who ...

What do the San Francisco 49ers and a cookie have in common? They both crumble when the pressure is on. For the second time this season, the 49ers waste another ...

The 30-year-old Kittle carries a 23-225-3 receiving line through four games ahead of a crucial matchup between NFC West contenders when the 49ers visit the Seahawks on Thursday.