An Aussie had a career day, and the rookie throwers are starting to make their mark as the NFL reached week five.

Nine teams scored 30-plus points and three games combined for 60 or more. Captain Kirk Cousins threw for a whopping 509 ...

The San Francisco 49ers were thought to be among the favorites to represent the NFC in the Super Bowl for a second straight year, but they haven't ...

The 49ers could've closed this game out 10 different ways. Instead they ended it looking as burned as the Levi's fans who ...

What do the San Francisco 49ers and a cookie have in common? They both crumble when the pressure is on. For the second time this season, the 49ers waste another ...

After swapping his cleats for a microphone, the spotlight during Sunday's game between the San Francisco 49ers and Arizona ...

The 49ers' biggest issue was something that's plagued them all season: They had six trips to the red zone and scored just one ...

The Madden Curse has once again cast its shadow, this time over San Francisco 49ers superstar Christian McCaffrey (CMC).

But the first series — a two-play, 72-yard touchdown drive, saw Campbell burned on a chunk-yard pass and then a 50-yard ...

The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

This was easily Purdy's worst fantasy game through weeks, but fantasy managers shouldn't panic about their quarterback the way 49ers' fans are panicking about their team's Super Bowl hopes.

SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...