The Madden Curse has once again cast its shadow, this time over San Francisco 49ers superstar Christian McCaffrey (CMC).

The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

The Arizona Cardinals and San Francisco 49ers play in Week 5 Sunday afternoon at Levi's Stadium with a 1:05 p.m. Arizona time ...

It's awfully early in the 2024 season still, but the San Francisco 49ers already have a sense of urgency. The 49ers lost to the Minnesota Vikings on Sunday, but they've also been losing key ...

Jennings (ankle) had two receptions (on four targets) for 37 yards in Sunday's 23-17 loss to Minnesota. Jennings carried a questionable tag through the practice week after picking up an ankle ...

Minnesota Vikings wide receiver Justin Jefferson's 97-yard touchdown reception in the Vikings' 23-17 win over the San Francisco 49ers was the longest scoring play of Week 2 through Sunday.

San Francisco 49ers star tight end George Kittle was carted off the field against the Minnesota Vikings. The good news is that Kittle just needed an IV because he was cramping. George Kittle #85 ...

The San Francisco 49ers picked up their first loss of the season, falling 23-17 to the Minnesota Vikings in Week 2. A special teams error, two turnovers (interception and fumble) and two turnovers ...

The Minnesota Vikings will host the San Francisco 49ers this Sunday at U.S. Bank Stadium in Minneapolis for week two of the NFL's regular season. Kickoff is scheduled for 1 p.m. ET and the game ...

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The San Francisco 49ers didn't violate the NFL's rules regarding the injury status of star running back Christian McCaffrey in Week 1, the league announced on Friday. "We have looked into the ...