The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

The Madden Curse has once again cast its shadow, this time over San Francisco 49ers superstar Christian McCaffrey (CMC).

The Arizona Cardinals and San Francisco 49ers play in Week 5 Sunday afternoon at Levi's Stadium with a 1:05 p.m. Arizona time ...

The San Francisco 49ers will wear alternate throwback uniforms that feature white pants to prepare for projected record-breaking temperatures during the team's Week 5 matchup with the Arizona ...

The 49ers called their win over the Patriots this past Sunday a work of art. Was it really, though? NFL.com's Eric Edholm wasn't impressed. That's why he placed the 49ers 12th in his Week 5 power ...

The San Francisco 49ers have begun to turn the page to their younger players. They signaled those changes in their Week 4 victory against the New England Patriots. Rookie safety Malik Mustapha got ...

As the San Francisco 49ers gear up for another run at a Super Bowl title, they find themselves with some unexpected holes to fill. All season, the 49ers' roster has been decimated by injuries ...

The San Francisco 49ers are back on track following their dominant 30-13 win over the New England Patriots and now find themselves in the top ten of the NFL power rankings of several national outlets.

San Francisco 49ers star offensive tackle Trent Williams isn't contemplating retirement just yet. "I don't think I'm going to put an expiration date on it," Williams said Tuesday during an ...

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The San Francisco 49ers are reinforcing the roster with two new additions, while also opening up the practice window for DL Kalia Davis. The injury bug has struck the 49ers over the past four ...