The 49ers' biggest issue was something that's plagued them all season: They had six trips to the red zone and scored just one ...

Cardinals quarterback Kyler Murray made big plays with his arm and his legs, running back James Conner fought for some tough yardage, and on the 49ers’ last offensive play, Brock Purdy got drilled as ...

The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

Half of the 10 Sunday afternoon games on the Week 5 NFL schedule are divisional matchups, but oddly, none of them features a ...

SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...

There are many ways for the San Francisco 49ers to defeat the Arizona Cardinals. But there is one way that is the most beneficial to them. The 49ers have to est ...

San Francisco's defense rebounded against the Patriots but faces a tougher test in Murray's dynamic playmaking ability. Brock ...

Using Samuel in the backfield isn’t a novel concept, but it’s one the 49ers have gone away from since his breakout All-Pro ...

The San Francisco 49ers have some depth issues on defense, and the Philadelphia Eagles may possess the solution.

Reeling from a last-minute loss to the Rams, the 49ers needed a game to find themselves. New England served as a necessary sparring partner for the Niners in a ...

Christian McCaffrey and Olivia Culpo have purchased a new house. TMZ Sports reported that the newlyweds purchased actor ...