A different, more optimized version of the molecule, called PX578, has been advanced to the clinic. That compound recently entered Phase 1 trials.

Before receiving a kidney transplant, patients with autosomal dominant polycystic kidney disease often undergo a nephrectomy. But there hasn’t been clear guidance on who’s a good candidate ...

The Icahn School of Medicine at Mount Sinai has launched the AI Small Molecule Drug Discovery Center, a bold endeavor that harnesses artificial intelligence (AI) to revolutionize drug development.

UCLA scientists have developed a molecule, PP405, that may reverse hair loss by reactivating dormant follicles. Early trials show promising results, and more testing is underway, with FDA approval ...

Plus, we answer questions from The Morning Filter’s audience. We sell different types of products and services to both investment professionals and individual investors. These products and ...

A team of researchers from McMaster University has identified a new molecule – lariocidin – that can challenge some of the most drug-resistant bacteria on Earth. The discovery responds to a critical ...

1. ACE Inhibitors and ARBs Angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are classes of drugs commonly prescribed for blood pressure and heart conditions.

In this regard, the renin-angiotensin system (RAS ... and situational stressors. The precise molecular mechanisms involved in Ang-(1-7) actions should also continue to be explored, particularly ...

Collectively, in the present study, we have elucidated the presence of Ang II-responsive molecular clock in rodent adrenal ZG cells and adrenocortical H295R cells. Because of the diversity of ...

A small molecule shaped like a lasso may be a powerful tool in the fight against infectious diseases. A small molecule shaped like a lasso may be a powerful tool in the fight against infectious ...