FILSPARI is the only Dual Endothelin Angiotensin Receptor Antagonist ... 50% of maximum label dose and maximally tolerated angiotensin-converting enzyme (ACE) inhibitors or ARB therapy.

For the safety analysis, patients were included if they had undergone randomization, were without critical Good Clinical Practice violations, and had taken ≥1 dose ... angiotensin-converting enzyme; ...

In contrast, ARBs would be expected to inhibit the biologic effects of angiotensin II more completely than ACE inhibitors, since they block the pathway more distally at the level of the receptor ...

The authors hypothesized that initial treatment with a combination angiotensin receptor blocker/diuretic agent would be safe and more effective than initial treatment with a single agent for these ...

Further optimization of the receptor blocker Researchers have since further optimized the substance, making it even more effective while also increasing its duration of effect for suitability as a ...

Single-dose baloxavir reduces household influenza transmission. ScienceDaily . Retrieved May 19, 2025 from www.sciencedaily.com / releases / 2025 / 04 / 250425113801.htm ...

Genetic and epidemiological evidence indicates that triglyceride-rich lipoproteins are causal risk factors for ...

The compound blocks a receptor on certain defense cells, thus preventing a derailed immune response. The study findings have been published in the journal Signal Transduction and Targeted Therapy.

Amicus Therapeutics reported a larger-than-expected loss for Q1 2025, with earnings per share (EPS) at -$0.16, missing the forecast of -$0.02. The company’s revenue also fell short of ...