New mechanisms discovered that show how development-dependent disruptions in mitochondrial function lead to premature skeletal aging.

Purdue University scientists have identified the Supinoxin small-molecule drug as a possible new therapy for small-cell lung ...

Mitochondria can internalize into different receptor cells, and can be injected externally to alleviate ... are poorly understood and are still solely evaluated at the animal model level. The ...

Without it, the mitochondria cannot function normally ... So far, the molecule has been studied in cells from patients as well as in animal models. Sebastian Valenzuela, a doctoral student at ...

Without it, the mitochondria cannot function normally ... So far, the molecule has been studied in cells from patients as well as in animal models. Sebastian Valenzuela, a doctoral student at ...

Scientists at Johns Hopkins Medicine say they have discovered how a group of proteins linked to Parkinson's disease and amyotrophic lateral sclerosis act as "guardians" of mitochondria, small ...

There’s unexpected movement in the world of cell biology — specifically, with the energy factories known as mitochondria. Ever since they were discovered in the mid-nineteenth century ...

However, sometimes the DNA within parts of the cell known as mitochondria becomes damaged, which can lead to serious diseases. Professor Pla-Martín from the Institute of Biochemistry and Molecular ...

That’s why Professor Suzannah Williams and her team have been working on an innovative, non-invasive technique to collect live animal cells — through their poop. The project, aptly named, the Poo Zoo, ...

Damage to the genetic material of mitochondria—the mitochondrial DNA ... Such damage also speeds up the aging process. However, the cells are normally capable of identifying such damage and ...

Animal models offer more insights into disease mechanisms than ... that humans and domestic or farm animals share a number of diseases, including those due to cell degeneration. Disorders like ...

It was found to accumulate selectively in the mitochondria, the "powerhouses" of the cells. The advantage of this method is that no labeling, which could distort the result, is needed. This gives ...