Adenosine activates astrocyte glucose metabolism and supply of energy to neurons to ensure that synaptic function (neurotransmitters passing communication signals between cells) continues apace ...

Comparing reactive astrocyte RNA-Seq datasets from Alzheimer’s, multiple sclerosis, Huntington’s, amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Parkinson’s brain revealed a ...

PET imaging of reactive astrocyte-neuron interaction reveals new insights into Alzheimer's disease pathology, offering a potential breakthrough in diagnosis and treatment Recently, a team of South ...

A drug that restores brain metabolism in mouse models of Alzheimer's also improved cognitive function. ... ANDREASSON: The astrocytes are kind of put to sleep, but you got to wake them up, ...

Dysregulated central-energy metabolism is a hallmark of brain aging. Supplying enough energy for neurotransmission relies on the neuron-astrocyte metabolic network.

A new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle ...

The astrocyte–neuron lactate-shuttle hypothesis states that lactate, once released into the extracellular space by astrocytes, can be up-taken and metabolized by neurons. This review focuses on this ...

These results suggest that acetate, previously considered an astrocyte-specific energy source, can facilitate reactive astrogliosis and contribute to the suppression of neuronal metabolism.

"Most people focus on neurons, but there are actually more astrocytes in the brain than neurons. Once the metabolism of astrocytes becomes perturbed, then the astrocyte definitely will not be able ...