Research led by the Department of General and Visceral Surgery, Faculty of Medicine, University of Freiburg, Germany has ...

Background and aims: Hydrophobic bile acids contribute to hepatocellular injury in cholestasis and rapidly induce apoptosis in vitro; however, unlike Fas agonists, cholestasis does not cause extensive ...

To investigate the hypocholesterolemic mechanism of barley in vivo, six-week-old C57BL/6J mice were fed a high-fat diet (HFD) or high-fat diet containing barley (HFD-B) for seven weeks. Total and LDL ...

Nutritionist Olivia Haas suggests dietary changes for gallbladder health. She recommends foods to reduce pain and dissolve ...

Cite this: The Intestinal Absorption of Biliary and Dietary Cholesterol as a Drug Target for Lowering the Plasma Cholesterol Level - Medscape - Jan 01, 2003.

The human apical sodium-dependent bile acid transporter (hASBT) may serve as a prodrug target for oral drug absorption. Synthetic, biological, NMR, and computational approaches identified the ...

In contrast, ezetimibe and its analogs are relatively small molecular structures that do not affect the enterohepatic flux of bile acids, but rather appear to act by disrupting the uptake of ...

Bile acids (BAs) have traditionally been viewed as mere ‘detergent’ molecules responsible for absorption of dietary fats and lipid-soluble vitamins. However, over the past decade, research in the ...

Background: Barrett’s oesophagus is a premalignant condition associated with an increased risk for the development of oesophageal adenocarcinoma (ADCA). Previous studies indicated that oxidative ...

Normally, bile salts are excreted into the duodenum entirely in the conjugated form, 9 in which they promote the normal absorption of fat in the proximal small intestine. 10 When fat absorption is ...

Calcium oxalate stones are associated with an imbalance in the intestinal oxalate metabolising flora: specific intestinal bacteria such as Oxalobacter formigenes, Lactobacillus and Bifidobacterium are ...

The incomplete absorption of bile acids from the distal ileum and the renal proximal tubule of Tcf1−/− mice indicated that Tcf1 might also be a transcriptional activator of genes involved in ...