Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood ...

Pulmonary rehabilitation is initiated and completed by a greater proportion of patients with IPF vs COPD or other chronic respiratory disorders.

Background Prior work suggests different interstitial lung diseases (ILDs) that share the radiological usual interstitial pneumonia (UIP) pattern have an overall worse prognosis. However, ...

Forced vital capacity (FVC) declined from baseline to 1 year by 98.6 mL and 84.6 mL on average with the 18-mg and 9-mg doses of the drug, respectively, compared with a decline of 165.8 mL in the ...

Qureight used three deep learning models developed to quantify lung volume (Lung8), pulmonary vessel volume (Vascul8), and fibrosis extent (Fibr8) on the baseline and follow-up CTs of ENV-101 ...

Avalyn Showcases Clinical Data Across Multiple Pulmonary Fibrosis Programs at ATS 2025 Provided by GlobeNewswire May 20, 2025, 1:01:00 PM ...

Background A polymorphism (rs35705950) 3 kb upstream of MUC5B , the gene encoding Mucin 5 subtype B, has been shown to be associated with familial and sporadic idiopathic pulmonary fibrosis (IPF). We ...

In one 2019 retrospective cohort study, data from 372 patients in the Pulmonary Fibrosis Foundation Patient Registry were analyzed to assess factors associated with delayed diagnosis of IPF. 9 The ...

PET IMAGING IN PULMONARY FIBROSIS 18 F-FDG is the most studied PET probe in IPF. It is purported to detect the increased metabolic activity of inflammatory cells and activated fibroblasts, although it ...

KEYWORDS: Mixed Connective Tissue Disease, Pulmonary Hypertension, Interstitial Lung Disease, Pulmonary Artery Diameter, Lung Parenchymal Abnormalities JOURNAL NAME: Open Journal of Medical Imaging, ...

Dr Jeffrey Swigris and Janet Talbert discuss the current understanding of the genetics of pulmonary fibrosis, explore the identified genetic pathways, and discuss future research directions.