Carboxylesterase-Triggered Theranostic Agent: Advancing Near-Infrared Imaging and Therapeutic Efficacy in Hepatocellular Carcinoma. Click to copy article link Article link copied! Fan Zheng. Fan Zheng ...

Four functional AO genes, carboxylesterase activity in blood, dopamine oxidized by MAO-A, FMO1 is the dominant hepatic FMO, no quaternary N-glucuronide formation: Dog: ...

ABSTRACT: The review provides an overview of the approaches, applications, and methods for ester prodrugs. Ester prodrugs are pharmacologically inactive compounds in their original form but become ...

For many plants, more branches means more fruit. But what causes a plant to grow branches? New research from the University of California, Davis shows how plants break down the hormone strigolactone, ...

In this study, we identified the lipases and carboxylesterases from 13 available sequenced S. cellulosum genomes and characterized a novel family VIII carboxylesterase LipB, which was alkali-tolerant, ...

Three carboxylesterase (CXE)-like enzymes from Catharanthus roseus and Tabernanthe iboga catalyze regio- and enantiodivergent [4+2] cycloaddition reactions to generate the aspidosperma (tabersonine ...

Renal or serum TG and TC levels were measured with kits per manufacturer's instructions (both from Jiancheng Bio.). Carboxylesterase activity of renal tissue or cultured cells was measured using a ...

Researchers from the East China University of Science and Technology in Shanghai have developed a new phenazine-based near-infrared fluorescent probe to detect intracellular carboxylesterases, the ...

Previous studies have found an abnormal expression of carboxylesterase in Wolman disease and other disorders. Wolman disease is caused by loss-of-function mutations in the LIPA gene, resulting in the ...

The carboxylesterase is a phase-1 detoxification enzyme that mainly hydrolyses organophosphates, carbamates, and synthetic pyrethroids. The quantitative mechanisms underlying metabolic resistance is ...