A number of comparative studies have been performed with metoprolol, a β 1-selective "second-generation" β blocker, and carvedilol, a nonselective and vasodilatative "third-generation" β blocker.

Chronic HCV infection is the leading cause of liver cancer in the US, Europe and Japan. “Dosing the first patient in our global Phase 3 program is a major advancement as we work to deliver a ...

CERo Therapeutics received FDA approval for its IND CMC amendment, crucial for starting CER-1236 patient dosing. The phase 1 trial will assess CER-1236's safety and efficacy in relapsed or refractory ...

An independent data monitoring committee (DMC) favors continuing dosing Elevidys (delandistrogene moxeparvovec-rokl) to people with Duchenne muscular dystrophy (DMD) in ongoing clinical trials, ...

“Given that the results significantly deviated from the predicted range and the absence of empiric data to further inform dose adjustment, the risk/benefit no longer supports continued dosing, and we ...

Pediatric doses associated with consistent exposure across age are still unknown. Therefore, we aim to identify a dosing strategy for ivermectin treatment in both pre-school-aged children (2–5 years ...

Humira is prescribed to treat multiple conditions. Your Humira dosing schedule will differ depending on the condition you’re using the drug to treat. Weekly dosing is used for some conditions ...

dosing—compared to weekly or even daily injections currently on the market. This first-in-class therapy works by reducing antithrombin, a protein that delays blood clotting, and significantly ...

Second, the duration of carvedilol dosing and dosage in the study animals were not consistent and may have influenced the results of the study. In addition, medications already administered at the ...

NPM-139 treatment resulted in nearly 20% placebo-adjusted weight loss from a single administration with expected once or twice-yearly dosing NPM-139 is a miniature, subdermal implant in ...

An internationally standardised, evidenced- and consensus-based approach to the dosing cancer patients with abnormal kidney function was much needed resource clinically, and adoption into regulatory ...

However, it has been found that additional α-adrenergic blockade with carvedilol may increase the number of patients with hemodynamic responses resulting in a reduction in hepatic venous pressure ...