For example, the genetic defect underlying common variable immune deficiency (CVID) is known in only 5–10% of the cases (3). At the same time, the phenotypic paradigm of PIDs has been challenged.

Early diagnosis and appropriate immunoglobulin (Ig) replacement therapy are fundamental for the favorable clinical outcome of common variable immunodeficiency (CVID) patients. Patients with ...

Over the last couple of years, stress started interrupting my sleep. I found myself having difficulty falling asleep and, even when I did, waking up in the middle of the night. As a freelancer who ...

In particular, mutations in TYK2 (tyrosine kinase 2) have been identified in one patient with autosomal recessive HIES, whereas the more common autosomal dominant variant is caused by dominant ...

They tested a combination of an SSRI and anti-PD-1 antibody -- a common immune checkpoint blockade, or ICB, therapy -- in mouse models of melanoma and colon cancer. ICB therapies work by blocking ...

They tested a combination of an SSRI and anti-PD-1 antibody — a common immune checkpoint blockade, or ICB, therapy — in mouse models of melanoma and colon cancer. ICB therapies work by ...

Big outbreaks of tornadoes, like the ones in Kentucky and Missouri over the weekend when lots of storms move across a large area in a short period of time, are getting more common. "In the past we ...

Hail is most common during spring and summer when a few key ingredients are present: warm, humid air near the surface; an unstable air mass in the middle troposphere; winds strongly changing with ...

The 56 year-old Dallasite has common variable immune deficiency, a condition that prevents her immune system from producing antibodies. Staying home was the only way Stein could keep safe.

The 56 year-old Dallasite has common variable immune deficiency, a condition that prevents her immune system from producing antibodies. Staying home was the only way Stein could keep safe.