Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, ...

Mitochondrial DNA has long been treated as a workhorse record of cellular history, but new research suggests it also hides a subtle and previously overlooked form of damage. By uncovering this cryptic ...

American geneticist who shared a Nobel Prize for discovering the double helix structure of DNA. Born on April 6, 1928 in Chicago, IL, USA, he died aged 97 years in East Northport on Long Island, NY, ...

Discover the emergence of dual-payload ADCs and PDCs, which could mark a significant evolution in targeted therapeutics.

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Transmembrane signaling is essential for cellular communication, yet reconstituting ...

It is important to have an artificial self-replication system that undergoes exponential growth enabling modeling and control of competition, evolution, and directed evolution. Here, we introduce a ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Measurement of the conformation of DNA in protein–DNA complexes is important to ...

A team has used a process known as DNA origami to make electrochemical sensors that can quickly detect and measure biomarkers. Using an approach called DNA origami, scientists at Caltech have ...

Next-generation sequencing (NGS) has made analyzing DNA faster and cheaper, with effects felt in the lab, clinic, and beyond. A set of newly-launched technologies are offering a twist on the chemistry ...

Dr. Isaac Li, along with students David Bakker and Micah Yang, prepare an experiment as they work to understand counter-intuitive biological interaction—like catch bonds—and how cells physically ...