The 49ers just blew another 10-point fourth quarter lead and lost 24-23 to the Arizona Cardinals. Now the 49ers are 2-3. Here ...

We’re now five weeks into the NFL season, and there are far more questions than answers for the San Francisco 49ers.

San Francisco veteran kicker Jake Moody suffered a high right ankle sprain while attempting to make a tackle on a kick return ...

SANTA CLARA—The West Coast heatwave wreaked havoc on the 49ers’ practice schedule this past week, leading coach Kyle Shanahan ...

The 49ers are a 7.5-point favorite over the Cardinals in NFL Week 5 odds for the game, courtesy of BetMGM Sportsbook. San ...

San Francisco has given the U.S. its first female House speaker, longest-serving female senator and, if Vice President Kamala ...

San Francisco 49ers running back Christian McCaffrey won't return in Week 6, but will likely make his long-awaited comeback ...

The San Francisco Giants are about to enter a new era of baseball in the Bay Area with the firing of Farhan Zaidi and subsequent hiring of franchise legend Bust ...

Protesters hit the streets of San Francisco Sunday, calling for an end to Israel’s war against Hamas, a year since Hamas’s ...

The San Francisco 49ers will be without second-year kicker Jake Moody for an extended period. Following Sunday's narrow 24-23 ...

The San Francisco 49ers dropped to 2-3 on the season after a 24-23 Week 5 loss to the Arizona Cardinals at Levi's Stadium in ...

What do the San Francisco 49ers and a cookie have in common? They both crumble when the pressure is on. For the second time this season, the 49ers waste another ...