Proteomics Approaches to Analysis of the Cytoskeleton in Immune Cells Cytoskeletal proteins are often identified in many proteomic studies either as contaminants, owing to their very high abundance, ...

The cytoplasm of eukaryotic cells contains an elaborate filamentous protein meshwork — the cytoskeleton — which comprises three distinct but integrated fibrous polymers: filamentous actin (F-actin; ...

The study of pathways that trigger apoptosis and ageing is crucial for increasing our understanding of these fundamental processes. Whereas apoptosis is probably triggered by a range of both ...

Actin filaments (F-actin) are key components of sarcomeres, the basic contractile units of skeletal muscle myofibrils. A crucial step during myofibril differentiation is the sequential exchange of ...

This is a preview. Log in through your library . Abstract We have established an in vitro assay for assembly of the cortical actin cytoskeleton of budding yeast cells. After permeabilization of yeast ...

Cells are characterized to be stable yet highly flexible. They constantly modify their shape and even move through tissue. These vital properties are based on a dynamically organized network of ...

An international team of researchers led by John Landers, PhD, at UMass Medical School, and Bryan Traynor, MD, PhD, at the National Institute on Aging at the National Institutes of Health (NIH), has ...

Using only a few ingredients, a biophysicist and his team have successfully implemented a minimalistic model of the cell that can change its shape and move on its own. They describe how they turned ...

Robert Mauck, PhD, from the University of Pennsylvania, discussed how aging and differentiation alter nuclear mechanobiology at the 2014 American Society of Bone and Mineral Research Conference in ...

Despite its importance in immune defense, the cytoskeleton in immune cells has not been a very popular target for proteomics studies, with only a few publications thus far. A variety of immune cell ...