Amber Salzman, Ph.D., CEO at Epicrispr Biotechnologies, joined the Business of Biotech live in Boston to talk about ...

This study demonstrates that Setd2 overexpression rescues bivalent gene expression during zygotic genome activation (ZGA) in ...

The research revealed widespread disruptions in the activity of genes responsible for early embryonic genome activation, metabolic processes, epigenetic regulation, and chromatin structure in embryos ...

The findings, published in Nature Cancer, identified two distinct epigenetic states that arise during development and are linked to cancer risk.

Epigenetics regulates gene expression through modifications, impacting health and disease. Aberrant patterns can lead to conditions like cancer and depression.

Scientists at the IMB have identified 5-formylcytosine (5fC) as an activating epigenetic mark that initiates gene expression in early vertebrate development. This discovery challenges previous notions ...

They found epigenetic changes in the blood of a group of 540 people without the disease and they linked this to the future development of type 2 diabetes in half of the individuals.

In contrast, individuals whose mothers were exposed to famine later during pregnancy did not contain these epigenetic marks. This means that the specific stage of her offspring’s development during ...

Northwestern Medicine studies published in Nature Cell Biology and Molecular Cell are improving the understanding of epigenetic mechanisms in cancer development and progression, as well as ...

Unfortunately, epigenetic changes can serve as a double-edged sword, because the same mechanisms that drive antigen-nonspecific, cross-protective beneficial immunity can also underlie detrimental ...