Currently dopamine replacement medications, like levodopa and dopamine agonists, are the primary treatment for Parkinson's ...

Fifty years of outstanding neuroscience research studies have revealed many secrets of how drugs of abuse affect and change ...

But we reach a point where the patient has lost most of their dopaminergic neurons and there is not much more that can be offered today to help the individual.

Dopaminergic neurons are essential for regulating a wide range of functions, including reward processing, learning, and locomotion. A specific subset – dopaminergic descending neurons (DADNs) – ...

Understanding how new neurons affect brain function throughout adulthood can offer new approaches to treating epilepsy and dementia. When you purchase through links on our site, we may earn an ...

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 14 on July 19, 2024, entitled, "Lipid ...

Dopaminergic neurons (green) in the ventral tegmental area, are involved in learning, motivation, and reward processing, and are altered in many neuropsychiatric disorders. Min Qiao Almost immediately ...

A11 dopaminergic neurons regulate somatosensory transduction by projecting from the diencephalon to the spinal cord, but the function of this descending projection in itch remained elusive. Here, we ...

Dopaminergic neurons with distinct projection patterns and physiological properties compose memory subsystems in a brain. However, it is poorly understood whether or how they interact during complex ...

Title: Directed Differentiation of Dopaminergic Neurons from Human Induced Pluripotent Stem Cells through Microfluidic Cell Squeeze ® Delivery of Multiple mRNA Encoding Transcription Factors ...

Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor. Nature Communications, 2022; 13 (1) DOI: 10.1038/s41467-022-29075-0 ...

Credit: DOI: 10.1016/j.celrep.2021.109975 Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons with an increased vulnerability to degeneration.