The 49ers along with their fans are going to be sweating it out in their red and gold for Sunday's game against the Cardinals ...

The San Francisco 49ers are loaded with plenty of top-tier talent but may not be able to keep the entire core together. San Francisco entered the season among the top contenders to win the Super ...

San Francisco 49ers wide receiver Deebo Samuel will be sidelined the next few weeks. On Monday, 49ers coach Kyle Shanahan told reporters that Samuel will miss "a couple weeks" due to a calf strain ...

The San Francisco 49ers and Los Angeles Rams play on Sunday, Sept. 22, at SoFi Stadium in a game on the NFL Week 3 schedule. Which team will win the Week 3 NFL game? The 49ers are a 7.5-point ...

That's why Bleacher Report's NFL Scouting Department feels that Cleveland should pursue San Francisco 49ers linebacker Dre Greenlaw in free agency next offseason. Bleacher Report's NFL staff notes ...

The San Francisco 49ers struggled to defend Justin Jefferson in Week 2. Although Jefferson was an opponent on Sunday, the 49ers wanted to recruit him in the offseason, according to ESPN.

and he brought that confidence to the team's home opener against the San Francisco 49ers on Sunday. After his defense came up with a big fourth-down stop, Darnold was back on his own 3-yard line ...

After a big Week 1 win over the New York Jets, the 49ers will hit the road to face the Minnesota Vikings in Week 2 with kickoff at 1 p.m. ET on Sunday. If you're looking where to catch the action ...

He's the biggest reason the 49ers ultimately won't win the Super Bowl. Grant Cohn has covered the San Francisco 49ers daily since 2011. He spent the first nine years of his career with the Santa ...

The San Francisco 49ers really don't like playing in Minnesota. They haven't won in the Gopher State since 1992. On Sunday, the trend continued with Sam Darnold's Minnesota Vikings getting the ...

The Minnesota Vikings will host the San Francisco 49ers this Sunday at U.S. Bank Stadium in Minneapolis for week two of the NFL's regular season. Kickoff is scheduled for 1 p.m. ET and the game ...

The 49ers and Vikings had two of the Top 5 most impressive wins during Week 1 of the NFL season, but only one can come away 2-0 when these squads meet at U.S. Bank Stadium in Minneapolis, Minnesota on ...