Willis will receive his Pro Football Hall of Fame Ring of Excellence on Sunday when the 49ers face the Cardinals.

Kyler Murray threw three TD passes, two to Greg Dortch in a 37-27 upset win in a Madden simulation of the Week 5 game.

SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...

The Arizona Cardinals and San Francisco 49ers will kick off Sunday afternoon from Levi’s Stadium at 1:05 p.m. Arizona time.

Analyzing Sunday’s Arizona Cardinals at San Francisco 49ers odds and lines, with expert NFL picks and predictions.

Preview the Week 5 matchup between the San Francisco 49ers and Arizona Cardinals with predictions, odds, over/under, spread, ...

This was the first week that players placed on injury lists before the season opener could be brought back to practice and ...

Coach Kevin O'Connell said Wednesday that Hockenson, who started the season on the physically unable to perform list, would ...